Can loratadine be used in pregnancy?

Is loratadine safe in first trimester of pregnancy?

There is currently no concern that exposure to loratadine in early pregnancy is linked to birth defects in the baby.

Can loratadine cause birth defects?

Can taking loratadine during pregnancy cause birth defects? In every pregnancy, a woman starts out with a 3-5% chance of having a baby with a birth defect. This is called her background risk. It is unlikely that loratadine would cause an increased chance for birth defects.

Which antihistamines are safe during pregnancy?

To conclude first generation antihistamines such as chlorpheniramine, hydroxyzine, and dexchlorpheniramine are the safest among antihistamines to be used in pregnancy.

Is prednisolone safe in pregnancy?

Taking an oral corticosteroid like prednisone or prednisolone long-term during pregnancy has been associated with an increased chance for preterm delivery (delivery before 37 weeks of pregnancy) and/or lower birth weight than expected.

How quickly does loratadine work?

Loratadine reaches peak plasma concentration in 1-2 hours; the metabolite does so in 3-4 hours. Their respective elimination half-lives are about 10 and 20 hours. Onset of action is within 1 hour and duration is at least 24 hours. Once-daily dosing is recommended.

What pregnancy category is loratadine?

Safety of Over-the-Counter Antihistamines, Decongestants, and Expectorants in Pregnancy

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Medication Drug class Pregnancy risk category*
Cetirizine (Zyrtec) Second-generation (selective, nonsedating) antihistamine B
Loratadine (Claritin) Second-generation (selective, nonsedating) antihistamine B

Do antihistamines affect pregnancy?

Main findings from this study. Scientific research suggests that using most types of antihistamines during pregnancy is not linked to birth defects. Out of 54 studies examined, 9 studies showed potential links between certain antihistamines and certain birth defects.

Can antihistamines cause miscarriage?

Due to the role of histamine and its receptors in these processes, it is reasonable to conclude that antihistamine use may be associated with pregnancy outcomes such as spontaneous abortion (SAB) and preterm birth (PTB). Currently, there are no safety guidelines for the use of antihistamines during pregnancy.

Does loratadine cross the placenta?

Loratadine / pseudoephedrine Pregnancy Warnings

Loratadine: Animal studies at up to 150 times the maximum recommended human dose found no teratogenicity. It is unknown if it crosses the placenta, but it is probable with its low molecular weight (about 383).

Can a nursing mother take loratadine?

Loratadine or cetirizine are the antihistamine tablets recommended if you’re breastfeeding. They can have different brand names, so speak to your pharmacist for advice.

What are the side effects of loratadine?

Loratadine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • headache.
  • dry mouth.
  • nosebleed.
  • sore throat.
  • mouth sores.
  • difficulty falling asleep or staying asleep.
  • nervousness.
  • weakness.