Can lithium cause birth defects?
New York—The largest-ever study of birth defects in babies exposed to lithium found an elevated risk of major congenital malformations in fetuses after first-trimester exposure to the mental health drug.
When should I stop taking lithium before getting pregnant?
If a woman taking lithium becomes pregnant, consider stopping the medicine gradually over 4 weeks if she is well. Explain to her that: stopping medication may not remove the risk of fetal heart malformations.
Can taking lithium cause a miscarriage?
The rate of miscarriage was 16.4% in lithium-exposed pregnancies, versus 8.3% in the bipolar disorder comparison group, and 5.7% in nonteratogenic-exposed pregnancies.
What category is lithium in pregnancy?
Treatment typically involves administration of the element lithium, which has been classified as a class D drug (legal to use during pregnancy, but may cause birth defects) and is one of only thirty known teratogenic drugs.
Which is the safest mood stabilizer during pregnancy?
Lamotrigine has been recognized as the overall safest mood stabilizer when both maternal and fetal complications are reviewed.
What bipolar medications are safe during pregnancy?
Treatment Options for Women With Bipolar Disorder During Pregnancy
- Antiepileptic medications including carbamazepine, lamotrigine, and valproic acid; and.
- Atypical antipsychotic medications: aripiprazole, olanzapine, quetiapine, risperidone, and ziprasidone.
What can I take instead of lithium during pregnancy?
“Over the past couple of decades, lamotrigine has increasingly been used during pregnancy as an alternative treatment option to lithium, due to its more favorable reproductive profile,” wrote the current authors.
Is lithium safe in second trimester?
In summary, while women with bipolar disorder have an increased risk of obstetric complications, there seems no association between lithium use during pregnancy and pregnancy or delivery related outcomes.
Should a bipolar woman have a baby?
Most women with bipolar disorder have a healthy pregnancy and baby, but there are some risks to be aware of. You may become unwell during your pregnancy, but the risk is higher after you give birth. Women with bipolar disorder are more likely to get: postnatal depression.
Does lithium cause cleft palate?
Intragastric administration of lithium carbonate to pregnant rats immediately after confirmation of pregnancy resulted in high incidence of cleft palate, growth retardation, brain liquification and pulpy brain, hepatomegaly and digital abnormalities, when compared to the saline-treated controls.
Can lithium make your period late?
Just like any other drug, lithium to has side effects when used. Sometimes this comes in the form of missed or very light periods, while others may experience heavy menstrual bleeding (HMB). Headache went away, period came back.
Can I take Seroquel while pregnant?
“Pregnancy Category C: Risk Summary: There are no adequate and well-controlled studies of SEROQUEL use in pregnant women. In limited published literature, there were no major malformations associated with quetiapine exposure during pregnancy. In animal studies, embryo-fetal toxicity occurred.